HDFN and the clinical impact of specific antibodies

HDFN and the clinical impact of specific antibodies

There are many antibodies that are capable of causing HDFN. While the majority of these antibodies act in similar ways, there are unique aspects to each specific antibody, and they can have an impact on the clinical manifestation of HDFN and the child’s treatment plan. For example, anti-Kell is known to suppress the bone marrow leading to hyporegenerative anemia.

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