Allo Hope Foundation
Empowered mothers. Equipped providers.
Better outcomes for babies with HDFN.
What is Alloimmunization?
What is HDFN?
Maternal alloimmunization occurs when a woman makes red blood cell antibodies after being exposed to a blood type that is different from her own. These antibodies can cross the placenta during pregnancy and target her baby’s red blood cells, a disease called hemolytic disease of the fetus and newborn (HDFN). HDFN can have devastating consequences including anemia, hyperbilirubinemia, and fetal/neonatal death. With close monitoring and timely treatment, babies with HDFN have a very high survival rate.
Your Trusted Source for HDFN Information
Whether you are newly diagnosed, navigating pregnancy, preparing for care after birth, or supporting patients, start with evidence-based, practical resources designed to help you understand what comes next at every stage.
Just Diagnosed
A brief overview of HDFN risks, monitoring, and treatment options for newly diagnosed patients and their families
Calculators & Tools
Access calculators and charts for MCA scans, newborn bilirubin, laboratory values, and more.
Prenatal & Newborn Booklets
Practical guides
for HDFN during pregnancy and after birth.
for HDFN during pregnancy and after birth.
For Clinicians
Evidence-based resources rooted in patient-centered care. Clinical guidelines, care checklists, pocket guides, and more.
AHF In Action
Learn about our recent work and accomplishments
The Allo Podcast
Step inside the often overlooked world of maternal red blood cell alloimmunization and hemolytic disease of the fetus and newborn (HDFN) where real families, frontline clinicians, and lifesaving research intersect.
Each episode of The Allo Podcast brings you powerful patient stories, expert perspectives, and valuable insights for providers and care teams. Whether you’re a parent navigating a high-risk pregnancy or a provider caring for alloimmunized families, we break down complex information into language you can actually use.
Our goal is to educate, empower, and equip you to advocate for the best possible care, while building community, sharing hope, and yes… having a lot of fun along the way.
Empowering Patients to Advocate for the Right Care
WE’RE HERE TO HELP
Find Support
- Join Our Support Group
- Read patient stories
- Grief & Loss Resources
- Natural Conception Alternatives
- and more…
Patient Stories
JOIN THE FIGHT
Get Involved
Change in HDFN happens when patients share what they know, families participate in research, supporters invest in our lifesaving work, and more people understand why it matters. Come get involved with The Allo Hope Foundation and help more families find the care they need in time.
Blooddrive Tool Kit
Hosting a blood drive takes a little bit of work to make a lasting impact. Get information on how to get started.
Share Your Story
You can help other families dealing with alloimmunization and HDFN by sharing your story.
Participate in Research
Large scale studies on alloimmunized pregnancies are few and far between. Your help makes progress possible.