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What is Alloimmunization and HDFN?

Maternal alloimmunization occurs when a woman makes red blood cell antibodies as a result of foreign blood mixing. These antibodies can cross the placenta and attack the unborn child, a disease called hemolytic disease of the fetus and newborn (HDFN). HDFN can have devastating consequences including anemia, hyperbilirubinemia, and death. With close monitoring and timely treatment, babies with HDFN have a very high survival rate.

The Allo Hope Foundation was founded to educate and support families and providers who are navigating alloimmunization and HDFN.

About Us

Be an advocate for yourself, your patients, and your community by learning about this complex disease.


HDFN Booklets

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Education Is Key.

Are you a patient just learning about your antibodies? Start here for an introduction to what is happening in your body.

Start Here

Provider Resources.

Are you a provider looking for the most current, evidence-based guidelines for the management of alloimmunized pregnancies?

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Ways You Can Help

Current Research and Clinical Trials

Clinical Decision Support Tree

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Allo Stories

Journey with our families as they go through pregnancy dealing with alloimmunization and HDFN.

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The Allo Hope Foundation - Protecting babies, supporting families.

The Hope Connection - AHF's Quarterly Newsletter

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Mission Statement

Our mission is to prevent any harm, stillbirth or infant death caused by alloimmunization and HDFN. We are dedicated to providing patient advocacy, support and education while promoting research and improving healthcare practices for the condition.