Publications

Alloimmunization Research and Publications

*Featured publication: management of alloimmunization in pregnancy*

Moise KJ, Markham KB, Spinella PC, Sherwood MR, Robinson KA, Wilson LM, Malone J, Espinoza J, Dizon-Townson D, Mercer L, Miller R, Pereira L, Sciscione A, Shamshirsaz AA, Shanahan K, Snowise S, Trevett T, González Vélez JM, Weathersby B. A Clinical Practice Guideline for the Management of Pregnancy Alloimmunized to Red Blood Cell Antigens. JAMA Netw Open. 2025;8(11):e2544649. Read here.

A detailed publication showing recommended management for alloimmunized pregnancy. We encourage readers to access the “supplemental content” and scroll to Table 4 for a complete list of recommendations, practice points, and rationales.

Bozzi L, Mohan D, Barlassina A, Moeri M, Sherwood M, Krumme A, Janssen E. Lived Experiences with Pregnancies Affected by Severe Hemolytic Disease of the Fetus and Newborn (HDFN): An Interview Study. Ultrasound in Obstetrics & Gynecology. Conference abstract.

An interview study of 28 women who experienced severe HDFN, discussing care quality, daily life impact, and psychosocial burdens. This abstract is pending full publication.

Mohan D, Barlassina A, Boeri M, Sherwood M, Janssen EM, Krumme A, Bozzi LM. PCR12 Hemolytic Disease of the Fetus and Newborn (HDFN): A Mixed-Methods Preference Study. Value in Health. 2025 Jul 1;28(6):S311–2. Read here.

A survey study of 28 women focusing on treatment decision-making in HDFN.

Sherwood MR, Weathersby BM, Granger ME, Shanahan KA, Markham KB. Alloimmunization in Pregnancy: Patient-reported Quality of Care, Mental Health Effects, and Impact Upon Daily Life. American Journal of Perinatology Reports. 2025 Jul;15(03):e146–53. Read here.

A survey of 127 mothers examining mental health and quality-of-life impacts, including differences between severe and non-severe HDFN.

Sherwood MR, Weathersby BM, Granger Howard ME, Markham KB. Patient-Reported Disease Presentation, Interventions, and Outcomes in U.S. Pregnancies Affected by Alloimmunization. Children. 2025;12(7):822. Read here.

A survey of 200 pregnancies examining titers, antibody type, treatments, and outcomes, including fetal death cases.

Sherwood MR, Andrews J, Bahr TM, Josephson CD, Leeper CM, Moise KJ, Yazer MH, Polk TM, Spinella PC. Development of evidence-based guidelines for emergency resuscitation of females of childbearing potential. Vox Sanguinis. 2025 May;120(S1):42. Conference abstract.

A precursor to the practice guidelines, presenting the systematic review and Delphi consensus methodology.

Yazer MH, Spinella PC, Holcomb JB, Horvath S, Sherwood MR, Emery SP, Leonard JC, Leeper CM. A review of attitudes to urgent RhD-positive transfusions in female patients. Transfusion. 2024 Sep;64(9):1784–90. Read here.

A review summarizing patient and provider attitudes toward RhD-positive transfusion when RhD-negative blood is unavailable.

Sherwood MR, Moise KJ. Hemolytic Disease of the Fetus and Newborn. National Organization for Rare Disorders. May 6, 2024. Read here.

An explanation of HDFN intended for readers new to the disease.

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