Welcome to the Provider Pocket Guide, a trusted resource designed to support the OB/MFM community in navigating the complexities of managing maternal alloimmunization and Hemolytic Disease of the Fetus and Newborn (HDFN).

Though rare, HDFN remains a serious condition in obstetric care, but with the right tools and timely intervention, its potentially devastating effects are largely preventable. We understand the challenges providers face as they collaborate with a multidisciplinary team to ensure consistent, quality care for affected mothers and infants. This guide is here to equip providers with clear, evidence-based recommendations, empowering them to confidently manage alloimmunized pregnancies and protect the lives of their most vulnerable patients. Together, we can make a lasting impact on maternal and neonatal outcomes.