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What is Alloimmunization? What is HDFN?

Maternal alloimmunization occurs when a woman makes red blood cell antibodies after being exposed to a blood type that is different from her own. These antibodies can cross the placenta and attack her unborn child, a disease called Hemolytic Disease of the Fetus and Newborn (HDFN). HDFN can have devastating consequences including anemia, hyperbilirubinemia, and death. With close monitoring and timely treatment, babies with HDFN have a very high survival rate.

Be an advocate for yourself, your patients, and your community by learning about this complex disease.

The Allo Podcast

Step inside the often overlooked world of maternal red blood cell alloimmunization and hemolytic disease of the fetus and newborn (HDFN) where real families, frontline clinicians, and lifesaving research intersect.

Each episode of The Allo Podcast brings you powerful patient stories, expert perspectives, and valuable insights for providers and care teams. Whether you’re a parent navigating a high-risk pregnancy or a provider caring for alloimmunized families, we break down complex information into language you can actually use.

Our goal is to educate, empower, and equip you to advocate for the best possible care, while building community, sharing hope, and yes… having a lot of fun along the way.

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WE’RE HERE TO HELP

Find Support

  • Join Our Support Group
  • Read patient stories
  • Grief & Loss Resources
  • Natural Conception Alternatives
  • and more…

Patient Stories

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JOIN THE FIGHT

Get Involved

There are plenty of ways to get involved with The Allo Hope Foundation including sharing your story, participating in research, donations and more.

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Blooddrive Tool Kit

Hosting a blood drive takes a little bit of work to make a lasting impact. Get information on how to get started.

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Share Your Story

You can help other families dealing with alloimmunization and HDFN by sharing your story.

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Participate in Research

Large scale studies on alloimmunized pregnancies are few and far between. Your help makes progress possible.

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